Endocrine Abstracts

The tachykinin neurokinin B (NKB) has prominent roles in neuroendocrine function, behaviour and the control of reproductive processes, yet little is known about its evolution, potential splice variants or the manner in which it is processed. Indeed, the cloning of human TAC3 in 2000 revealed a single gene transcript encoding a single precursor and single tachykinin. Here, we deduce the phylogenetic relationship of a family of NKB peptides, and identify novel TAC3...